Tuesday, July 13, 2010

Glycosylated hemoglobin blood glucose control Dinglao

FDA (Food and Drug Administration U.S. Food and Drug Administration) has officially announced that there is not any clinical studies confirm that oral antidiabetic drugs can reduce the risk of cardiovascular disease. Experts point out that type 2 diabetes can lead to multiple complications, long-term effective control of blood sugar in type 2 diabetes treatment goals. If you can completely normal blood glucose control in the context of, you can delay or prevent diabetes complications. The glycated hemoglobin (HbA1C) is an internationally recognized diabetes control "gold standard."

More than half of type 2

Diabetes complications

Surveys show the country of type 2 diabetes blood glucose control in patients with less than 30% compliance rate. The glycemic control of chronic non-compliance will cause complications. More than half of patients with type 2 diabetes at least one kind of complications.

According to reports, up to 4 percent of people with diabetes can cause cataracts complicated; and renal microvascular complications of diabetes can lead to uremia; diabetic retinal microvascular complications can lead to blind. More noteworthy is that, cerebrovascular and cardiovascular complications in diabetic patients is the main reason for premature death, while the lower limbs of diabetic patients with vascular disease is caused by the main physical disability.

Experts pointed out that the complications of diabetes is not only a serious threat to the health of patients, patients returned to an enormous financial burden. Survey, there are complications in patients with type 2 diabetes are hospital charges and times the per capita direct medical costs of up to 4 times in patients without complications. In addition, type 2 diabetes per capita direct medical cost of 9115.1 yuan, accounting for the proportion of disposable income in Shanghai was 77.8%, to 177.9 percent in Xi'an. National City type 2 diabetes and its complications in patients with the total cost of 23.38 billion yuan.

Medication on time

Still need regular monitoring of blood glucose

"Some patients with diabetic complications and urgent demand, it is easy to fall into the fog of medication in the treatment without realizing it, have all kinds of medication errors." According to experts, some diabetes symptoms used to determine blood sugar under control is good or bad, feeling symptoms too obvious, stop medication. In fact, to estimate the disease symptoms alone is not reliable. Clinical practice, diet and exercise alone can get good control of blood sugar found only in a small number of less severe cases of type 2 diabetic patients, most patients with type 2 diabetes in the initial diagnosis, the need for medication.

Others believe that treatment of diabetic patients taking hypoglycemic drugs on time as long as there is no problem, this is a misunderstanding. Doctors cited an example: Most patients with hypertension is clear, the use of antihypertensive drugs at the same time, the need for regular monitoring of blood pressure to adjust the medication dosage and time. Diabetes as well. Blood glucose control is a life-long, under normal circumstances, when the guidance of a doctor with diabetes, the blood glucose control to a satisfactory level of after, blood sugar that situations sometimes Hui Yin Chuxianbodong, especially in certain exceptional circumstances (such as a more serious infection, excessive mental pressure and exercise, eating less, etc.), blood glucose too high or too low may occur the phenomenon. Thus, while patients take medication, need regular monitoring of blood glucose changes. "Note lifestyle and drug laws, long-term stability and good blood glucose control in diabetic patients is vital." Expert stressed.

Glycated hemoglobin is a "gold standard"

Some patients think that some oral hypoglycemic drugs can reduce the risk of cardiovascular disease, blindness choice of treatment drugs. The FDA recently announced: Up to now, there is no any clinical study confirmed that oral diabetes drugs can reduce the risk of cardiovascular disease.

Experts also pointed out that with the extension of course, many of the effect of sulfonylureas decreased, medicine called "secondary failure of antidiabetic drugs." Some patients do not pay attention periodic review, that has not stopped their treatment, psychological feeling of safety, but the emergence of drug secondary failure, in fact, tantamount to no treatment. Some patients have been eating the medicine, the result was complications occurred, the reason why.

Experts strongly caution patients: the right to focus on prevention and treatment of diabetic complications. Type 2 diabetes treatment goals are long term control of blood sugar. Patients should insist on testing blood sugar, one can understand the disease control as well as clinical outcomes, as well as the drug of choice and an important basis for dosage adjustment. Such as type 2 diabetes, Avandia is a long-term glycemic control in patients with heart medication.

Many patients in the current treatment of the effect of glycemic control are not satisfied with the urgent need to understand how long-term effective control of blood glucose. In response, experts said, glycated hemoglobin (HbA1C) is a measure of the level of blood sugar control "gold standard." Currently doctors are still monitoring the blood glucose and postprandial blood glucose fasting blood glucose as the main basis for prescription, these two indicators are usually expressed only short-term blood sugar levels; and HbA1C, the average life of up to 120 days, can reflect the fasting and postprandial comprehensive level of blood sugar. Study, HbA1C decreased by 1% each, can decrease the risk of diabetes, 21% of deaths, heart attacks decreased by 14%, 37% reduction in microvascular complications, peripheral vascular disease, 43% reduction. Therefore, long-term control of blood glucose lowering HbA1C is a top priority.

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